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In the past two decades, nanoscale advanced materials have been explored for biosensing molecules, so new horizons have opened up for identifying and quantifying biomolecules, and possible early diagnosis of diseases.DNA nanobiosensors show promise. This article provides an overview on their optical and electrochemical aspects. We discuss recent progress in this field, describing basic concepts of molecular beacons and quantum dots as optical nano-imaging systems. Also, carbon nanotubes provide a platform for development and advancement of electrochemical DNA nanobiosensors, which are increasingly being implemented as robust tools for detection in biomedical sciences.  相似文献   
13.
We give a combinatorial characterization of graphs whose normalized Laplacian has three distinct eigenvalues. Strongly regular graphs and complete bipartite graphs are examples of such graphs, but we also construct more exotic families of examples from conference graphs, projective planes, and certain quasi-symmetric designs.  相似文献   
14.
We generalize the concept of strong walk-regularity to directed graphs. We call a digraph strongly \(\ell \)-walk-regular with \(\ell > 1\) if the number of walks of length \(\ell \) from a vertex to another vertex depends only on whether the first vertex is the same as, adjacent to, or not adjacent to the second vertex. This generalizes also the well-studied strongly regular digraphs and a problem posed by Hoffman. Our main tools are eigenvalue methods. The case that the adjacency matrix is diagonalizable with only real eigenvalues resembles the undirected case. We show that a digraph \(\varGamma \) with only real eigenvalues whose adjacency matrix is not diagonalizable has at most two values of \(\ell \) for which \(\varGamma \) can be strongly \(\ell \)-walk-regular, and we also construct examples of such strongly walk-regular digraphs. We also consider digraphs with non-real eigenvalues. We give such examples and characterize those digraphs \(\varGamma \) for which there are infinitely many \(\ell \) for which \(\varGamma \) is strongly \(\ell \)-walk-regular.  相似文献   
15.
The main objective of this research work is to present analytical solutions for free vibration analysis of moderately thick rectangular plates, which are composed of functionally graded materials (FGMs) and supported by either Winkler or Pasternak elastic foundations. The proposed rectangular plates have two opposite edges simply-supported, while all possible combinations of free, simply-supported and clamped boundary conditions are applied to the other two edges. In order to capture fundamental frequencies of the functionally graded (FG) rectangular plates resting on elastic foundation, the analysis procedure is based on the first-order shear deformation plate theory (FSDT) to derive and solve exactly the equations of motion. The mechanical properties of the FG plates are assumed to vary continuously through the thickness of the plate and obey a power law distribution of the volume fraction of the constituents, whereas Poisson’s ratio is set to be constant. First, a new formula for the shear correction factors, used in the Mindlin plate theory, is obtained for FG plates. Then the excellent accuracy of the present analytical solutions is confirmed by making some comparisons of the results with those available in literature. The effect of foundation stiffness parameters on the free vibration of the FG plates, constrained by different combinations of classical boundary conditions, is also presented for various values of aspect ratios, gradient indices, and thickness to length ratios.  相似文献   
16.
In Iran, high school graduates enter university after taking a very difficult entrance exam called the Konkoor. Therefore, only the top-performing students are admitted by universities to continue their bachelor's education in statistics. Surprisingly, statistically, most of such students fall into the following categories: (1) do not succeed in their education despite their excellent performance on the Konkoor and in high school; (2) graduate with a grade point average (GPA) that is considerably lower than their high school GPA; (3) continue their master's education in majors other than statistics and (4) try to find jobs unrelated to statistics. This article employs the well-known and powerful statistical technique, the Bayesian structural equation modelling (SEM), to study the academic success of recent graduates who have studied statistics at Shahid Beheshti University in Iran. This research: (i) considered academic success as a latent variable, which was measured by GPA and other academic success (see below) of students in the target population; (ii) employed the Bayesian SEM, which works properly for small sample sizes and ordinal variables; (iii), which is taken from the literature, developed five main factors that affected academic success and (iv) considered several standard psychological tests and measured characteristics such as ‘self-esteem’ and ‘anxiety’. We then study the impact of such factors on the academic success of the target population. Six factors that positively impact student academic success were identified in the following order of relative impact (from greatest to least): ‘Teaching–Evaluation’, ‘Learner’, ‘Environment’, ‘Family’, ‘Curriculum’ and ‘Teaching Knowledge’. Particularly, influential variables within each factor have also been noted.  相似文献   
17.
Edged topological disorder in quantum mesoscopic cylinder threaded with magnetic flux is investigated by using exact diagonalization. The Fermi energy continuously varies with respect to magnetic flux against saw-tooth variation in ordered mesoscopic cylinder. In addition, the energy levels repel each other and energy gap appears in variation of energy spectra as a function of magnetic flux in edged topological disordered mesoscopic cylinder rather than ordered ones. In strong edged topological disorder, a narrow mesoscopic cylinder which is a low-dimensional sample behaves in the same way as a three-dimensional system.  相似文献   
18.
The nullity of a graph is the multiplicity of the eigenvalue zero in its spectrum. We obtain some lower bounds for the nullity of graphs and we then find the nullity of bipartite graphs with no cycle of length a multiple of 4 as a subgraph. Among bipartite graphs on n vertices, the star has the greatest nullity (equal to n − 2). We generalize this by showing that among bipartite graphs with n vertices, e edges and maximum degree Δ which do not have any cycle of length a multiple of 4 as a subgraph, the greatest nullity is . G. R. Omidi: This research was in part supported by a grant from IPM (No.87050016).  相似文献   
19.
A new nonlinear integral resonant controller (NIRC) is introduced in this paper to suppress vibration in nonlinear oscillatory smart structures. The NIRC consists of a first-order resonant integrator that provides additional damping in a closed-loop system response to reduce high-amplitude nonlinear vibration around the fundamental reso-nance frequency. The method of multiple scales is used to obtain an approximate solution for the closed-loop system. Then closed-loop system stability is investigated using the resulting modulation equation. Finally, the effects of different control system parameters are illustrated and an approximate solution response is verified via numerical simulation results. The advantages and disadvantages of the proposed controller are presented and extensively discussed in the results. The controlled system via the NIRC shows no high-amplitude peaks in the neighboring frequencies of the resonant mode, unlike conventional second-order compensation methods. This makes the NIRC controlled system robust to excitation frequency variations.  相似文献   
20.
Let M be an associated matrix of a graph G (the adjacency, Laplacian and signless Laplacian matrix). Two graphs are said to be cospectral with respect to M if they have the same M spectrum. A graph is said to be determined by M spectrum if there is no other non-isomorphic graph with the same spectrum with respect to M. It is shown that T-shape trees are determined by their Laplacian spectra. Moreover among them those are determined by their adjacency spectra are characterized. In this paper, we identify graphs which are cospectral to a given T-shape tree with respect to the signless Laplacian matrix. Subsequently, T-shape trees which are determined by their signless Laplacian spectra are identified.  相似文献   
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